Abstract
Competing for electrophiles: The elusive iron-catalyzed C-C coupling reaction was investigated and analyzed by a Hammett study of the nucleophilic partner. This required finding conditions in which the iron catalyst is stable in the presence of an excess of the Grignard reagent. The selectivity- determining step seems to be the transmetalation, occurring either before or after the oxidative addition step (see scheme).
| Original language | English |
|---|---|
| Pages (from-to) | 11991-11993 |
| Number of pages | 3 |
| Journal | Chemistry - A European Journal |
| Volume | 17 |
| Issue number | 43 |
| DOIs | |
| Publication status | Published - 17 Oct 2011 |
| Externally published | Yes |
Keywords
- catalysis
- coupling reactions
- Hammett plots
- iron
- reaction mechanisms
Programme Area
- Programme Area 2: Water Resources
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