Iron-catalyzed coupling of aryl grignard reagents with alkyl halides: A competitive hammett study

Anna Hedström, Ulla Bollmann, Jenny Bravidor, Per Ola Norrby

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

46 Citationer (Scopus)

Abstrakt

Competing for electrophiles: The elusive iron-catalyzed C-C coupling reaction was investigated and analyzed by a Hammett study of the nucleophilic partner. This required finding conditions in which the iron catalyst is stable in the presence of an excess of the Grignard reagent. The selectivity- determining step seems to be the transmetalation, occurring either before or after the oxidative addition step (see scheme).

OriginalsprogEngelsk
Sider (fra-til)11991-11993
Antal sider3
TidsskriftChemistry - A European Journal
Vol/bind17
Udgave nummer43
DOI
StatusUdgivet - 17 okt. 2011
Udgivet eksterntJa

Programområde

  • Programområde 2: Vandressourcer

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